Food Tech Startups Fight Global Cocoa Shortage With Lab-Grown Chocolate
Food tech startups and major confectionery brands are developing lab-grown cocoa and plant-based alternatives to combat severe global supply chain shortages and soaring prices.

A global chocolate crisis is driving food tech startups to reinvent the production of cocoa through cellular agriculture and sustainable plant-based alternatives. With cocoa prices soaring to historic highs and climate change threatening traditional farming, the industry is racing to secure the future of confectionery.
Lab-Grown Cocoa and Cellular Agriculture
Nearly a dozen startups in the US, Europe, Israel, and Asia are developing lab-grown cocoa and chocolate alternatives. Using biotechnology methods adapted from the pharmaceutical industry, companies like Celleste and California Cultured are growing cocoa cells in bioreactors. This approach bypasses traditional agriculture, requiring just two cocoa beans to produce quantities that would normally demand extensive land use.
Celleste, led by CEO Michelle Berse Golomb, has partnered with confectionery giant Mondelēz International to produce prototype chocolate bars. Meanwhile, California Cultured aims to commercialize its high-flavonol cocoa grown in cost-effective systems by 2028, targeting health-conscious consumers and addressing supply chain vulnerabilities.
Plant-Based Substitutes and Silent Replacements
While lab-grown chocolate works toward commercial viability, other companies are introducing non-cocoa alternatives made from upcycled agricultural waste. Voyage Foods produces cocoa-free chocolate using roasted grape seeds, sunflower protein flour, and vegetable fats. The company's massive Ohio facility can manufacture up to 10,000 tons of cocoa substitute annually, backed by agricultural giant Cargill.
Confectionery giants are also adapting to supply pressures. Hershey has quietly transitioned several popular products, including Mr. Goodbar and Rolo, from "milk chocolate" to "chocolate candy" after incorporating alternative fats. Industry experts emphasize that these innovations are essential to keep beloved treats accessible and affordable as traditional farming struggles to meet global demand.





